Tobias Buchborn | Systems Neuroscientist
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Research

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Psychedelic drugs make consciousness an experimental variable.

They provide a unique opportunity to study how defined molecular perturbations propagate across biological scales to reorganize brain dynamics and physiology, ultimately informing our understanding of multi-level homeostasis and mental health.

Below, five experimental research directions are outlined.

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LSD restores avoidance learning in a rat model of depression
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Differential tolerance to LSD and DMT occurs via 5-HT2A regulation
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Pyramidal cell dynamics of psychedelic head twitches in mice
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Thalamocortical glutamate release under psychedelics in rats (ongoing)
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Psilocybin in rat alcohol-seeking behaviour (ongoing)
© 2026 Tobias Buchborn
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